Interactions between Ivabradine and Grapefruit

Interactions between Ivabradine and Grapefruit

The potential interactions between Ivabradine and Grapefruit have been investigated. Ivabradine is a medication used for the treatment of heart rhythm disorders, while Grapefruit is a fruit that is rich in certain substances.

Mechanism of action of Ivabradine: Ivabradine lowers the heart rate by blocking the so-called If channels in the sinus node of the heart. This slows down the electrical conduction and reduces the heart rate.

Mechanism of action of Grapefruit: Grapefruit contains certain enzymes that can affect the metabolism of medications in the liver. This can lead to increased medication levels in the body.

Interactions:

• Ivabradine and Grapefruit together can influence the metabolism of Ivabradine in the liver, leading to increased Ivabradine levels and potential undesirable effects.

Ivabradine and Grapefruit together can influence the metabolism of Ivabradine in the liver, leading to increased Ivabradine levels and potential undesirable effects.

Notes and Warnings:

- This article is based on the current state until December 2021.

- Before taking Ivabradine and Grapefruit simultaneously, it is advisable to consult a doctor or pharmacist.